Diagnostic value of progesterone receptor and p53 expression in uterine smooth muscle tumors

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Diagnostic value of progesterone receptor and p53 expression in uterine smooth muscle tumors

BACKGROUND The diagnosis of uterine smooth muscle tumors depends on a combination of microscopic features. However, a small number of these tumors still pose difficult diagnostic challenges. AIM To investigate progesterone receptor (PR) and p53 expression in leiomyomas (LMs), atypical leiomyomas (ALMs), smooth muscle tumors of uncertain malignant potential (STUMP), and leiomyosarcomas (LMSs) ...

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Expression of Ki-67, P53 and progesterone receptors in uterine smooth muscle tumors. Diagnostic value.

Aim was to investigate expression of Ki-67, P53 and progesterone receptors (PR) in leiomyomas (LM), smooth muscle tumors of uncertain malignant potential (STUMP) and leiomyosarcomas (LMS) and to establish possible usefulness of these three parameters in distinguishing between LM and STUMP and STUMP and LMS. Retrospective study of 51 uterine smooth muscle neoplasm (16 LM, 18 STUMP, 17 LMS) techn...

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Diagnostic Value of Proliferatin Index Including MIB1 and Argyrophilic Nucleolar Organizer Regions Proteins in Uterine Smooth Muscle Tumors

  Background and Objectives: Uterine smooth muscle tumors are the most common human neoplasm .They are divided clinically as benign and malignant but there is  another group of  lesions which is difficult to place in these two categories ,so-called smooth  muscle tumors of uncertain malignant potential (STUMP) and differentiation  of these tumors on the basis of H&E staining is impossible . Th...

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diagnostic value of proliferatin index including mib1 and argyrophilic nucleolar organizer regions proteins in uterine smooth muscle tumors

background and objectives: uterine smooth muscle tumors are the most common human neoplasm .they are divided clinically as benign and malignant but there is  another group of  lesions which is difficult to place in these two categories ,so-called smooth  muscle tumors of uncertain malignant potential (stump) and differentiation  of these tumors on the basis of h&e staining is impossible . t...

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Enhanced expression of transient receptor potential channel 3 in uterine smooth muscle tissues of lipopolysaccharide-induced preterm delivery mice

Objective(s): We aimed to investigate the influence of transient receptor potential channel 3 (TRPC3) on lipopolysaccharide-induced (LPS) preterm delivery mice. Materials and Methods: Mice were randomly assigned to the four groups: an unpregnant group, a mid-pregnancy group (E15), a term delivery group, and an LPS-induced preterm delivery group (intraperitoneal injection LPS at 15 days). Uterin...

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ژورنال

عنوان ژورنال: Diagnostic Pathology

سال: 2012

ISSN: 1746-1596

DOI: 10.1186/1746-1596-7-1